What is missing from my garden soil?

Stop tilling and just add organic matter every year - make compost if you can, or buy bagged. Fork up the soil instead of tilling. Tilling turns the soil to powder and that will turn to clay that won't drain well. Don't bother with peat moss. It just mats up and ruins the soil structure. Make sure any manure is not from animals that have been wormed. Otherwise you're good to go!